MyD88-dependent pro-inflammatory activity in Vi polysaccharide vaccine against typhoid promotes Ab switching to IgG

Vi capsular polysaccharide is currently in use as a vaccine against human typhoid caused by Salmonella Typhi. The vaccine efficacy correlates with IgG anti-Vi Abs. We have recently reported that Vi can generate inflammatory responses through activation of the TLR2/TLR1 complex. In the present study,...

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Detalles Bibliográficos
Autores principales: Garg, Rohini, Akhade, Ajay Suresh, Yadav, Jitender, Qadri, Ayub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572389/
https://www.ncbi.nlm.nih.gov/pubmed/26303218
http://dx.doi.org/10.1177/1753425915599242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572389/
https://www.ncbi.nlm.nih.gov/pubmed/26303218
http://dx.doi.org/10.1177/1753425915599242

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