A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways

Gene-based, pathway, and other multivariate association methods are motivated by the possibility of GxG and GxE interactions; however, accounting for such interactions is limited by the challenges associated with adequate modeling information. Here we propose an easy-to-implement joint location-scal...

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Detalles Bibliográficos
Autores principales: Soave, David, Corvol, Harriet, Panjwani, Naim, Gong, Jiafen, Li, Weili, Boëlle, Pierre-Yves, Durie, Peter R., Paterson, Andrew D., Rommens, Johanna M., Strug, Lisa J., Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572492/
https://www.ncbi.nlm.nih.gov/pubmed/26140448
http://dx.doi.org/10.1016/j.ajhg.2015.05.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572492/
https://www.ncbi.nlm.nih.gov/pubmed/26140448
http://dx.doi.org/10.1016/j.ajhg.2015.05.015

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