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A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways
Gene-based, pathway, and other multivariate association methods are motivated by the possibility of GxG and GxE interactions; however, accounting for such interactions is limited by the challenges associated with adequate modeling information. Here we propose an easy-to-implement joint location-scal...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572492/ https://www.ncbi.nlm.nih.gov/pubmed/26140448 http://dx.doi.org/10.1016/j.ajhg.2015.05.015 |