Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

Identifying genomic annotations that differentiate causal from trait-associated variants is essential to fine mapping disease loci. Although many studies have identified non-coding functional annotations that overlap disease-associated variants, these annotations often colocalize, complicating the a...

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Detalles Bibliográficos
Autores principales: Trynka, Gosia, Westra, Harm-Jan, Slowikowski, Kamil, Hu, Xinli, Xu, Han, Stranger, Barbara E., Klein, Robert J., Han, Buhm, Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572568/
https://www.ncbi.nlm.nih.gov/pubmed/26140449
http://dx.doi.org/10.1016/j.ajhg.2015.05.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572568/
https://www.ncbi.nlm.nih.gov/pubmed/26140449
http://dx.doi.org/10.1016/j.ajhg.2015.05.016

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