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Hormetic effect of rotenone in primary human fibroblasts

BACKGROUND: Rotenone inhibits the electron transfer from complex I to ubiquinone, in this way interfering with the electron transport chain in mitochondria. This chain of events induces increased levels of intracellular reactive oxygen species, which in turn can contribute to acceleration of telomer...

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Detalles Bibliográficos
Autores principales: Marthandan, Shiva, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Diekmann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572608/
https://www.ncbi.nlm.nih.gov/pubmed/26380578
http://dx.doi.org/10.1186/s12979-015-0038-8