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The endogenous caspase-8 inhibitor c-FLIP(L) regulates ER morphology and crosstalk with mitochondria
Components of the death receptor-mediated pathways like caspase-8 have been identified in complexes at intracellular membranes to spatially restrict the processing of local targets. In this study, we report that the long isoform of the cellular FLICE-inhibitory protein (c-FLIP(L)), a well-known inhi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572861/ https://www.ncbi.nlm.nih.gov/pubmed/25501600 http://dx.doi.org/10.1038/cdd.2014.197 |