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The endogenous caspase-8 inhibitor c-FLIP(L) regulates ER morphology and crosstalk with mitochondria

Components of the death receptor-mediated pathways like caspase-8 have been identified in complexes at intracellular membranes to spatially restrict the processing of local targets. In this study, we report that the long isoform of the cellular FLICE-inhibitory protein (c-FLIP(L)), a well-known inhi...

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Detalles Bibliográficos
Autores principales: Marini, E S, Giampietri, C, Petrungaro, S, Conti, S, Filippini, A, Scorrano, L, Ziparo, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572861/
https://www.ncbi.nlm.nih.gov/pubmed/25501600
http://dx.doi.org/10.1038/cdd.2014.197