GnT1IP-L specifically inhibits MGAT1 in the Golgi via its luminal domain

Mouse GnT1IP-L, and membrane-bound GnT1IP-S (MGAT4D) expressed in cultured cells inhibit MGAT1, the N-acetylglucosaminyltransferase that initiates the synthesis of hybrid and complex N-glycans. However, it is not known where in the secretory pathway GnT1IP-L inhibits MGAT1, nor whether GnT1IP-L inhi...

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Detalles Bibliográficos
Autores principales: Huang, Hung-Hsiang, Hassinen, Antti, Sundaram, Subha, Spiess, Andrej-Nikolai, Kellokumpu, Sakari, Stanley, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572887/
https://www.ncbi.nlm.nih.gov/pubmed/26371870
http://dx.doi.org/10.7554/eLife.08916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572887/
https://www.ncbi.nlm.nih.gov/pubmed/26371870
http://dx.doi.org/10.7554/eLife.08916

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