Identification of novel mureidomycin analogues via rational activation of a cryptic gene cluster in Streptomyces roseosporus NRRL 15998

Antimicrobial agents are urgently needed to tackle the growing threat of antibiotic-resistant pathogens. An important source of new antimicrobials is the large repertoire of cryptic gene clusters embedded in microbial genomes. Genome mining revealed a napsamycin/mureidomycin biosynthetic gene cluste...

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Detalles Bibliográficos
Autores principales: Jiang, Lingjuan, Wang, Lu, Zhang, Jihui, Liu, Hao, Hong, Bin, Tan, Huarong, Niu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572928/
https://www.ncbi.nlm.nih.gov/pubmed/26370924
http://dx.doi.org/10.1038/srep14111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572928/
https://www.ncbi.nlm.nih.gov/pubmed/26370924
http://dx.doi.org/10.1038/srep14111

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