Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone

BACKGROUND: Molecular iodine (I(2)) exhibits antiproliferative and apoptotic effects on in vivo and in vitro cancer models. These effects are thought to be mediated by an iodinated arachidonic acid derivative, 6-iodolactone (6IL), and one of the proposed mechanisms is that 6IL activates Peroxisome P...

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Detalles Bibliográficos
Autores principales: Nava-Villalba, Mario, Nuñez-Anita, Rosa E., Bontempo, Alexander, Aceves, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573306/
https://www.ncbi.nlm.nih.gov/pubmed/26376791
http://dx.doi.org/10.1186/s12943-015-0436-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573306/
https://www.ncbi.nlm.nih.gov/pubmed/26376791
http://dx.doi.org/10.1186/s12943-015-0436-8

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