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Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

Glucocorticoids (GCs) have been widely used as coadjuvants in the treatment of solid tumours, but GC treatment may be associated with poor pharmacotherapeutic response or prognosis. The genomic action of GC in these tumours is largely unknown. Here we find that dexamethasone (Dex, a synthetic GC)-re...

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Detalles Bibliográficos
Autores principales: Chen, Zhong, Lan, Xun, Wu, Dayong, Sunkel, Benjamin, Ye, Zhenqing, Huang, Jiaoti, Liu, Zhihua, Clinton, Steven K., Jin, Victor X., Wang, Qianben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573460/
https://www.ncbi.nlm.nih.gov/pubmed/26374485
http://dx.doi.org/10.1038/ncomms9323