An intact helical domain is required for Gα(14) to stimulate phospholipase Cβ

BACKGROUND: Stimulation of phospholipase Cβ (PLCβ) by the activated α-subunit of G(q) (Gα(q)) constitutes a major signaling pathway for cellular regulation, and structural studies have recently revealed the molecular interactions between PLCβ and Gα(q). Yet, most of the PLCβ-interacting residues ide...

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Detalles Bibliográficos
Autores principales: Kwan, Dawna HT, Wong, Ka M., Chan, Anthony SL, Yung, Lisa Y., Wong, Yung H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573470/
https://www.ncbi.nlm.nih.gov/pubmed/26377666
http://dx.doi.org/10.1186/s12900-015-0043-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573470/
https://www.ncbi.nlm.nih.gov/pubmed/26377666
http://dx.doi.org/10.1186/s12900-015-0043-3

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