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The crystal structure of JNK from Drosophila melanogaster reveals an evolutionarily conserved topology with that of mammalian JNK proteins

BACKGROUND: The c-Jun N-terminal kinases (JNKs), members of the mitogen-activated protein kinase (MAPK) family, engage in diverse cellular responses to signals produced under normal development and stress conditions. In Drosophila, only one JNK member is present, whereas ten isoforms from three JNK...

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Detalles Bibliográficos
Autores principales: Chimnaronk, Sarin, Sitthiroongruang, Jatuporn, Srisucharitpanit, Kanokporn, Srisaisup, Monrudee, Ketterman, Albert J., Boonserm, Panadda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573485/
https://www.ncbi.nlm.nih.gov/pubmed/26377800
http://dx.doi.org/10.1186/s12900-015-0045-1