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Single Amino Acid Polymorphisms of Pertussis Toxin Subunit S2 (PtxB) Affect Protein Function

Whooping cough due to Bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations. Polymorphisms in the pertussis toxin, ptxA and ptxB genes, and the pertactin, prn genes of clinical isolates of Bordetell...

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Detalles Bibliográficos
Autores principales: Millen, Scott H., Watanabe, Mineo, Komatsu, Eiji, Yamaguchi, Fuminori, Nagasawa, Yuki, Suzuki, Eri, Monaco, Haleigh, Weiss, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573519/
https://www.ncbi.nlm.nih.gov/pubmed/26375454
http://dx.doi.org/10.1371/journal.pone.0137379