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Down-regulation of microRNA-26a and up-regulation of microRNA-27a contributes to aggressive progression of human osteosarcoma

BACKGROUND: Osteosarcoma is the most common primary bone malignancy with high local aggressiveness and rapid metastasizing potential, resulting in poor survival. Increasing reports suggest that deregulated microRNAs (miRNAs) might provide novel therapeutic targets for cancers. However, the expressio...

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Detalles Bibliográficos
Autores principales: Taheriazam, Afshin, Bahador, Reza, Karbasy, Seyyed Hasan, Jamshidi, Seyed Mir Mansoor Moazen, Torkaman, Ali, Yahaghi, Emad, Shakeri, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573687/
https://www.ncbi.nlm.nih.gov/pubmed/26377680
http://dx.doi.org/10.1186/s13000-015-0400-3