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Why the Central Dogma: on the nature of the great biological exclusion principle

ABSTRACT: The Central Dogma of molecular biology posits that transfer of information from proteins back to nucleic acids does not occur in biological systems. I argue that the impossibility of reverse translation is indeed a major, physical exclusion principle that emerges due to the transition from...

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Detalles Bibliográficos
Autor principal: Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573691/
https://www.ncbi.nlm.nih.gov/pubmed/26377089
http://dx.doi.org/10.1186/s13062-015-0084-3