Pathogenic Mechanism of an Autism-Associated Neuroligin Mutation Involves Altered AMPA-Receptor Trafficking

Neuroligins are postsynaptic cell-adhesion molecules that bind to presynaptic neurexins. Although the general synaptic role of neuroligins is undisputed, their specific functions at a synapse remain unclear, even controversial. Moreover, many neuroligin gene mutations were associated with autism, bu...

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Detalles Bibliográficos
Autores principales: Chanda, Soham, Aoto, Jason, Lee, Sung-Jin, Wernig, Marius, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573762/
https://www.ncbi.nlm.nih.gov/pubmed/25778475
http://dx.doi.org/10.1038/mp.2015.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573762/
https://www.ncbi.nlm.nih.gov/pubmed/25778475
http://dx.doi.org/10.1038/mp.2015.20

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