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A negative loop within the nuclear pore complex controls global chromatin organization

The nuclear pore complex (NPC) tethers chromatin to create an environment for gene regulation, but little is known about how this activity is regulated to avoid excessive tethering of the genome. Here we propose a negative regulatory loop within the NPC controlling the chromatin attachment state, in...

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Detalles Bibliográficos
Autores principales: Breuer, Manuel, Ohkura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573852/
https://www.ncbi.nlm.nih.gov/pubmed/26341556
http://dx.doi.org/10.1101/gad.264341.115