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A negative loop within the nuclear pore complex controls global chromatin organization
The nuclear pore complex (NPC) tethers chromatin to create an environment for gene regulation, but little is known about how this activity is regulated to avoid excessive tethering of the genome. Here we propose a negative regulatory loop within the NPC controlling the chromatin attachment state, in...
Autores principales: | Breuer, Manuel, Ohkura, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573852/ https://www.ncbi.nlm.nih.gov/pubmed/26341556 http://dx.doi.org/10.1101/gad.264341.115 |
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