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Regulation of gene expression dynamics during developmental transitions by the Ikaros transcription factor

The DNA-binding protein Ikaros is a potent tumor suppressor and hematopoietic regulator. However, the mechanisms by which Ikaros functions remain poorly understood, due in part to its atypical DNA-binding properties and partnership with the poorly understood Mi-2/NuRD complex. In this study, we anal...

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Detalles Bibliográficos
Autores principales: Arenzana, Teresita L., Schjerven, Hilde, Smale, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573854/
https://www.ncbi.nlm.nih.gov/pubmed/26314708
http://dx.doi.org/10.1101/gad.266999.115