Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?

The coordination of tissue function is mediated by gap junctions (GJs) that enable direct cell-cell transfer of metabolic and electric signals. GJs are formed by connexin (Cx) proteins of which Cx43 is most widespread in the human body. Beyond its role in direct intercellular communication, Cx43 als...

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Detalles Bibliográficos
Autores principales: De Bock, Marijke, Wang, Nan, Decrock, Elke, Bultynck, Geert, Leybaert, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573893/
https://www.ncbi.nlm.nih.gov/pubmed/26424967
http://dx.doi.org/10.1155/2015/257471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573893/
https://www.ncbi.nlm.nih.gov/pubmed/26424967
http://dx.doi.org/10.1155/2015/257471

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