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Non-structural protein NS3/NS3a is required for propagation of bluetongue virus in Culicoides sonorensis

BACKGROUND: Bluetongue virus (BTV) causes non-contagious haemorrhagic disease in ruminants and is transmitted by Culicoides spp. biting midges. BTV encodes four non-structural proteins of which NS3/NS3a is functional in virus release. NS3/NS3a is not essential for in vitro virus replication. However...

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Detalles Bibliográficos
Autores principales: Feenstra, Femke, Drolet, Barbara S., Boonstra, Jan, van Rijn, Piet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573936/
https://www.ncbi.nlm.nih.gov/pubmed/26383094
http://dx.doi.org/10.1186/s13071-015-1063-3