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Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors

BACKGROUND: This study aims to further evaluate the specificity and selectivity of [(18)F]FTC-146 and obtain additional data to support its clinical translation. METHODS: The binding of [(19)F]FTC-146 to vesicular acetylcholine transporter (VAChT) was evaluated using [(3)H]vesamicol and PC12(A123.7)...

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Detalles Bibliográficos
Autores principales: Shen, Bin, James, Michelle L., Andrews, Lauren, Lau, Christopher, Chen, Stephanie, Palner, Mikael, Miao, Zheng, Arksey, Natasha C., Shuhendler, Adam J., Scatliffe, Shawn, Kaneshige, Kota, Parsons, Stanley M., McCurdy, Christopher R., Salehi, Ahmad, Gambhir, Sanjiv S., Chin, Frederick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573970/
https://www.ncbi.nlm.nih.gov/pubmed/26384292
http://dx.doi.org/10.1186/s13550-015-0122-2