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Systematic synergy modeling: understanding drug synergy from a systems biology perspective

Owing to drug synergy effects, drug combinations have become a new trend in combating complex diseases like cancer, HIV and cardiovascular diseases. However, conventional synergy quantification methods often depend on experimental dose–response data which are quite resource-demanding. In addition, t...

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Detalles Bibliográficos
Autores principales: Chen, Di, Liu, Xi, Yang, Yiping, Yang, Hongjun, Lu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574089/
https://www.ncbi.nlm.nih.gov/pubmed/26377814
http://dx.doi.org/10.1186/s12918-015-0202-y