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Systematic synergy modeling: understanding drug synergy from a systems biology perspective
Owing to drug synergy effects, drug combinations have become a new trend in combating complex diseases like cancer, HIV and cardiovascular diseases. However, conventional synergy quantification methods often depend on experimental dose–response data which are quite resource-demanding. In addition, t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574089/ https://www.ncbi.nlm.nih.gov/pubmed/26377814 http://dx.doi.org/10.1186/s12918-015-0202-y |