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Optimization of yeast-based production of medicinal protoberberine alkaloids

BACKGROUND: Protoberberine alkaloids are bioactive molecules abundant in plant preparations for traditional medicines. Yeast engineered to express biosynthetic pathways for fermentative production of these compounds will further enable investigation of the medicinal properties of these molecules and...

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Detalles Bibliográficos
Autores principales: Galanie, Stephanie, Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574094/
https://www.ncbi.nlm.nih.gov/pubmed/26376732
http://dx.doi.org/10.1186/s12934-015-0332-3