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Integrated isotope-assisted metabolomics and (13)C metabolic flux analysis reveals metabolic flux redistribution for high glucoamylase production by Aspergillus niger

BACKGROUND: Aspergillus niger is widely used for enzyme production and achievement of high enzyme production depends on the comprehensive understanding of cell’s metabolic regulation mechanisms. RESULTS: In this paper, we investigate the metabolic differences and regulation mechanisms between a high...

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Detalles Bibliográficos
Autores principales: Lu, Hongzhong, Liu, Xiaoyun, Huang, Mingzhi, Xia, Jianye, Chu, Ju, Zhuang, Yingping, Zhang, Siliang, Noorman, Henk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574132/
https://www.ncbi.nlm.nih.gov/pubmed/26383080
http://dx.doi.org/10.1186/s12934-015-0329-y