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Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) in the common marmoset monkey (Callithrix jacchus) is a relevant preclinical model for translational research into immunopathogenic mechanisms operating in multiple sclerosis (MS). Prior studies showed a core pathogenic role of T and B cell...

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Detalles Bibliográficos
Autores principales: Jagessar, S. Anwar, Heijmans, Nicole, Blezer, Erwin L A, Bauer, Jan, Weissert, Robert, ‘t Hart, Bert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574133/
https://www.ncbi.nlm.nih.gov/pubmed/26377397
http://dx.doi.org/10.1186/s12974-015-0378-5