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Three-pathway combination for glutathione biosynthesis in Saccharomyces cerevisiae

BACKGROUND: Glutathione (GSH), a pivotal non-protein thiol, can be biosynthesized through three pathways in different organisms: (1) two consecutive enzymatic reactions catalyzed by γ-glutamylcysteine synthetase (Gsh1 or GshA) and glutathione synthetase (Gsh2 or GshB); (2) a bifunctional γ-glutamylc...

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Detalles Bibliográficos
Autores principales: Tang, Liang, Wang, Weiwei, Zhou, Wenlong, Cheng, Kai, Yang, Yan, Liu, Minzhi, Cheng, Kedi, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574134/
https://www.ncbi.nlm.nih.gov/pubmed/26377681
http://dx.doi.org/10.1186/s12934-015-0327-0