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Cellular Defense Enzyme Drives Exceptionally High Rate of Mutation in HIV

HIV-1 is already known to have an extremely fast mutation rate, but a new study shows it to be more than two orders of magnitude higher than previously believed, and that this is largely due to host cytidine deaminases. Read the Research Article.

Detalles Bibliográficos
Autor principal: Robinson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574152/
https://www.ncbi.nlm.nih.gov/pubmed/26375682
http://dx.doi.org/10.1371/journal.pbio.1002252