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A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppression

BACKGROUND: Role of epigenetic mechanisms towards regulation of the complex life cycle/pathogenesis of Plasmodium falciparum, the causative agent of malaria, has been poorly understood. To elucidate stage-specific epigenetic regulation, we performed genome-wide mapping of multiple histone modificati...

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Detalles Bibliográficos
Autores principales: Karmodiya, Krishanpal, Pradhan, Saurabh J., Joshi, Bhagyashree, Jangid, Rahul, Reddy, Puli Chandramouli, Galande, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574195/
https://www.ncbi.nlm.nih.gov/pubmed/26388940
http://dx.doi.org/10.1186/s13072-015-0029-1