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Inhibition of Excessive Cell Proliferation by Calcilytics in Idiopathic Pulmonary Arterial Hypertension

Idiopathic pulmonary arterial hypertension (IPAH) is a rare and progressive disease of unknown pathogenesis. Vascular remodeling due to excessive proliferation of pulmonary arterial smooth muscle cells (PASMCs) is a critical pathogenic event that leads to early morbidity and mortality. The excessive...

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Detalles Bibliográficos
Autores principales: Yamamura, Aya, Ohara, Naoki, Tsukamoto, Kikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574199/
https://www.ncbi.nlm.nih.gov/pubmed/26375676
http://dx.doi.org/10.1371/journal.pone.0138384