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Impaired survival of regulatory T cells in pulmonary sarcoidosis

BACKGROUND: Impaired regulatory T cell (Treg) function is thought to contribute to ongoing inflammatory responses in sarcoidosis, but underlying mechanisms remain unclear. Moreover, it is not known if increased apoptotic susceptibility of Tregs may contribute to an impaired immunosuppressive functio...

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Detalles Bibliográficos
Autores principales: Broos, Caroline E., van Nimwegen, Menno, Kleinjan, Alex, ten Berge, Bregje, Muskens, Femke, in ’t Veen, Johannes C.C.M., Annema, Jouke T., Lambrecht, Bart N., Hoogsteden, Henk C., Hendriks, Rudi W., Kool, Mirjam, van den Blink, Bernt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574219/
https://www.ncbi.nlm.nih.gov/pubmed/26376720
http://dx.doi.org/10.1186/s12931-015-0265-8