Cyclosporine A Treatment Inhibits Abcc6-Dependent Cardiac Necrosis and Calcification following Coxsackievirus B3 Infection in Mice

Coxsackievirus type B3 (CVB3) is a cardiotropic enterovirus. Infection causes cardiomyocyte necrosis and myocardial inflammation. The damaged tissue that results is replaced with fibrotic or calcified tissue, which can lead to permanently altered cardiac function. The extent of pathogenesis among in...

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Detalles Bibliográficos
Autores principales: Marton, Jennifer, Albert, Danica, Wiltshire, Sean A., Park, Robin, Bergen, Arthur, Qureshi, Salman, Malo, Danielle, Burelle, Yan, Vidal, Silvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574283/
https://www.ncbi.nlm.nih.gov/pubmed/26375467
http://dx.doi.org/10.1371/journal.pone.0138222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574283/
https://www.ncbi.nlm.nih.gov/pubmed/26375467
http://dx.doi.org/10.1371/journal.pone.0138222

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