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Absence of association between Plasmodium falciparum small sub-unit ribosomal RNA gene mutations and in vitro decreased susceptibility to doxycycline

BACKGROUND: Doxycycline is an antibiotic used in combination with quinine or artesunate for malaria treatment or alone for malaria chemoprophylaxis. Recently, one prophylactic failure has been reported, and several studies have highlighted in vitro doxycycline decreased susceptibility in Plasmodium...

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Detalles Bibliográficos
Autores principales: Gaillard, Tiphaine, Wurtz, Nathalie, Houzé, Sandrine, Sriprawat, Kanlaya, Wangsing, Chirapat, Hubert, Véronique, Lebras, Jacques, Nosten, François, Briolant, Sébastien, Pradines, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574345/
https://www.ncbi.nlm.nih.gov/pubmed/26377329
http://dx.doi.org/10.1186/s12936-015-0878-x