Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics

Microtubule dynamics and polarity stem from the polymerization of αβ-tubulin heterodimers. Five conserved tubulin cofactors/chaperones and the Arl2 GTPase regulate α- and β-tubulin assembly into heterodimers and maintain the soluble tubulin pool in the cytoplasm, but their physical mechanisms are un...

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Detalles Bibliográficos
Autores principales: Nithianantham, Stanley, Le, Sinh, Seto, Elbert, Jia, Weitao, Leary, Julie, Corbett, Kevin D, Moore, Jeffrey K, Al-Bassam, Jawdat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574351/
https://www.ncbi.nlm.nih.gov/pubmed/26208336
http://dx.doi.org/10.7554/eLife.08811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574351/
https://www.ncbi.nlm.nih.gov/pubmed/26208336
http://dx.doi.org/10.7554/eLife.08811

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