Transforming Growth Factor Beta (TGF-β) Is a Muscle Biomarker of Disease Progression in ALS and Correlates with Smad Expression

We recently identified Smads1, 5 and 8 as muscle biomarkers in human ALS. In the ALS mouse, these markers are elevated and track disease progression. Smads are signal transducers and become activated upon receptor engagement of ligands from the TGF-β superfamily. Here, we sought to characterize liga...

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Detalles Bibliográficos
Autores principales: Si, Ying, Kim, Soojin, Cui, Xiangqin, Zheng, Lei, Oh, Shin J., Anderson, Tina, AlSharabati, Mohammad, Kazamel, Mohamed, Volpicelli-Daley, Laura, Bamman, Marcas M., Yu, Shaohua, King, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574401/
https://www.ncbi.nlm.nih.gov/pubmed/26375954
http://dx.doi.org/10.1371/journal.pone.0138425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574401/
https://www.ncbi.nlm.nih.gov/pubmed/26375954
http://dx.doi.org/10.1371/journal.pone.0138425

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