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Major depressive disorder as a nonlinear dynamic system: bimodality in the frequency distribution of depressive symptoms over time
BACKGROUND: A defining characteristic of Major Depressive Disorder (MDD) is its episodic course, which might indicate that MDD is a nonlinear dynamic phenomenon with two discrete states. We investigated this hypothesis using the symptom time series of individual patients. METHODS: In 178 primary car...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574448/ https://www.ncbi.nlm.nih.gov/pubmed/26385384 http://dx.doi.org/10.1186/s12888-015-0596-5 |