Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain

BACKGROUND: Botulism is a naturally occurring disease, mainly caused by the ingestion of food contaminated by the botulinum neurotoxins (BoNTs). Botulinum neurotoxins are the most lethal. They are classified among the six major biological warfare agents by the Centers for Disease Control. BoNTs act...

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Detalles Bibliográficos
Autores principales: Avril, Arnaud, Miethe, Sebastian, Popoff, Michel R., Mazuet, Christelle, Chahboun, Siham, Rasetti-Escargueil, Christine, Sesardic, Dorothea, Thullier, Philippe, Hust, Michael, Pelat, Thibaut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574468/
https://www.ncbi.nlm.nih.gov/pubmed/26382731
http://dx.doi.org/10.1186/s12896-015-0206-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574468/
https://www.ncbi.nlm.nih.gov/pubmed/26382731
http://dx.doi.org/10.1186/s12896-015-0206-0

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