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Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A(1) and A(2) by targeting their heavy chain
BACKGROUND: Botulism is a naturally occurring disease, mainly caused by the ingestion of food contaminated by the botulinum neurotoxins (BoNTs). Botulinum neurotoxins are the most lethal. They are classified among the six major biological warfare agents by the Centers for Disease Control. BoNTs act...
Autores principales: | Avril, Arnaud, Miethe, Sebastian, Popoff, Michel R., Mazuet, Christelle, Chahboun, Siham, Rasetti-Escargueil, Christine, Sesardic, Dorothea, Thullier, Philippe, Hust, Michael, Pelat, Thibaut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574468/ https://www.ncbi.nlm.nih.gov/pubmed/26382731 http://dx.doi.org/10.1186/s12896-015-0206-0 |
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