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Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials

BACKGROUND: Trials in Alzheimer’s disease are increasingly focusing on prevention in asymptomatic individuals. This poses a challenge in examining treatment effects since currently available approaches are often unable to detect cognitive and functional changes among asymptomatic individuals. Result...

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Detalles Bibliográficos
Autores principales: Dodge, Hiroko H., Zhu, Jian, Mattek, Nora C., Austin, Daniel, Kornfeld, Judith, Kaye, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574479/
https://www.ncbi.nlm.nih.gov/pubmed/26379170
http://dx.doi.org/10.1371/journal.pone.0138095