Cargando…
Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials
BACKGROUND: Trials in Alzheimer’s disease are increasingly focusing on prevention in asymptomatic individuals. This poses a challenge in examining treatment effects since currently available approaches are often unable to detect cognitive and functional changes among asymptomatic individuals. Result...
Autores principales: | Dodge, Hiroko H., Zhu, Jian, Mattek, Nora C., Austin, Daniel, Kornfeld, Judith, Kaye, Jeffrey A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574479/ https://www.ncbi.nlm.nih.gov/pubmed/26379170 http://dx.doi.org/10.1371/journal.pone.0138095 |
Ejemplares similares
-
Reproducibility and replicability of high‐frequency, in‐home digital biomarkers in reducing sample sizes for clinical trials
por: Wu, Chao‐Yi, et al.
Publicado: (2021) -
In-Home Mobility Frequency and Stability in Older Adults Living Alone With or Without MCI: Introduction of New Metrics
por: Wu, Chao-Yi, et al.
Publicado: (2021) -
Correlating continuously captured home-based digital biomarkers of daily function with postmortem neurodegenerative neuropathology
por: Hantke, Nathan C., et al.
Publicado: (2023) -
Time Out-of-Home and Cognitive, Physical, and Emotional Wellbeing of Older Adults: A Longitudinal Mixed Effects Model
por: Petersen, Johanna, et al.
Publicado: (2015) -
Characteristics associated with willingness to participate in a randomized controlled behavioral clinical trial using home-based personal computers and a webcam
por: Dodge, Hiroko H, et al.
Publicado: (2014)