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Characterization of an African trypanosome mutant refractory to lectin-induced death

Incubation of African trypanosomes with the lectin concanavalin A (conA) leads to alteration in cellular DNA content, DNA degradation, and surface membrane blebbing. Here, we report the generation and characterization of a conA-refractory Trypanosoma brucei line. These insect stage parasites were re...

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Detalles Bibliográficos
Autores principales: Hackler, Amber L., Qiu, Yijian, Patrick, Stephen L., Hee Lee, Soo, Acosta-Serrano, Alvaro, Morris, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574508/
https://www.ncbi.nlm.nih.gov/pubmed/26393238
http://dx.doi.org/10.1016/j.bbrep.2015.08.013