Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9

Retinal pigment epithelial (RPE) cell death is a hallmark of age-related macular degeneration. The alternative pathway of complement activation is strongly implicated in RPE cell dysfunction and loss in age-related macular degeneration; therefore, it is critical that RPE cells use molecular strategi...

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Detalles Bibliográficos
Autores principales: Georgiannakis, Apostolos, Burgoyne, Tom, Lueck, Katharina, Futter, Clare, Greenwood, John, Moss, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2015
Materias:
Innate Immunity and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574521/
https://www.ncbi.nlm.nih.gov/pubmed/26324770
http://dx.doi.org/10.4049/jimmunol.1500937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574521/
https://www.ncbi.nlm.nih.gov/pubmed/26324770
http://dx.doi.org/10.4049/jimmunol.1500937

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