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Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9

Retinal pigment epithelial (RPE) cell death is a hallmark of age-related macular degeneration. The alternative pathway of complement activation is strongly implicated in RPE cell dysfunction and loss in age-related macular degeneration; therefore, it is critical that RPE cells use molecular strategi...

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Detalles Bibliográficos
Autores principales:	Georgiannakis, Apostolos, Burgoyne, Tom, Lueck, Katharina, Futter, Clare, Greenwood, John, Moss, Stephen E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Innate Immunity and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574521/ https://www.ncbi.nlm.nih.gov/pubmed/26324770 http://dx.doi.org/10.4049/jimmunol.1500937

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