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Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data

Analysis of Hi-C data has shown that the genome can be divided into two compartments called A/B compartments. These compartments are cell-type specific and are associated with open and closed chromatin. We show that A/B compartments can reliably be estimated using epigenetic data from several differ...

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Detalles Bibliográficos
Autores principales: Fortin, Jean-Philippe, Hansen, Kasper D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574526/
https://www.ncbi.nlm.nih.gov/pubmed/26316348
http://dx.doi.org/10.1186/s13059-015-0741-y