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EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation

BACKGROUND: Endocytosis of activated EGF receptor (EGFR) to specific endocytic compartments is required to terminate EGF signaling. Trafficking of EGFR relies on microtubule tracks that transport the cargo vesicle to their intermediate and final destinations and can be modulated through posttranslat...

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Detalles Bibliográficos
Autores principales: Lee, Seung Joon, Li, Zhiqin, Litan, Alisa, Yoo, Soonmoon, Langhans, Sigrid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574528/
https://www.ncbi.nlm.nih.gov/pubmed/26382850
http://dx.doi.org/10.1186/s12860-015-0070-8