Cargando…
EGF-induced sodium influx regulates EGFR trafficking through HDAC6 and tubulin acetylation
BACKGROUND: Endocytosis of activated EGF receptor (EGFR) to specific endocytic compartments is required to terminate EGF signaling. Trafficking of EGFR relies on microtubule tracks that transport the cargo vesicle to their intermediate and final destinations and can be modulated through posttranslat...
Autores principales: | Lee, Seung Joon, Li, Zhiqin, Litan, Alisa, Yoo, Soonmoon, Langhans, Sigrid A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574528/ https://www.ncbi.nlm.nih.gov/pubmed/26382850 http://dx.doi.org/10.1186/s12860-015-0070-8 |
Ejemplares similares
-
Inhibition of epidermal growth factor signaling by the cardiac glycoside ouabain in medulloblastoma
por: Wolle, Daniel, et al.
Publicado: (2014) -
Cancer as a channelopathy: ion channels and pumps in tumor development and progression
por: Litan, Alisa, et al.
Publicado: (2015) -
Na,K-ATPase β(1)-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity
por: Lee, Seung Joon, et al.
Publicado: (2015) -
Sonic Hedgehog-Induced Histone Deacetylase Activation Is Required for Cerebellar Granule Precursor Hyperplasia in Medulloblastoma
por: Lee, Seung Joon, et al.
Publicado: (2013) -
Highly Acetylated Tubulin Permits Enhanced Interactions with and Trafficking of Plasmids Along Microtubules
por: Badding, Melissa A., et al.
Publicado: (2012)