Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells

BACKGROUND: Dexamethasone suppressed inflammation and haemodynamic changes in an animal model of pulmonary arterial hypertension (PAH). A major target for dexamethasone actions is NF-κB, which is activated in pulmonary vascular cells and perivascular inflammatory cells in PAH. Reverse remodelling is...

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Detalles Bibliográficos
Autores principales: Price, Laura C., Shao, Dongmin, Meng, Chao, Perros, Frederic, Garfield, Benjamin E., Zhu, Jie, Montani, David, Dorfmuller, Peter, Humbert, Marc, Adcock, Ian M., Wort, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574531/
https://www.ncbi.nlm.nih.gov/pubmed/26382031
http://dx.doi.org/10.1186/s12931-015-0262-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574531/
https://www.ncbi.nlm.nih.gov/pubmed/26382031
http://dx.doi.org/10.1186/s12931-015-0262-y

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