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Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells

BACKGROUND: Dexamethasone suppressed inflammation and haemodynamic changes in an animal model of pulmonary arterial hypertension (PAH). A major target for dexamethasone actions is NF-κB, which is activated in pulmonary vascular cells and perivascular inflammatory cells in PAH. Reverse remodelling is...

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Detalles Bibliográficos
Autores principales:	Price, Laura C., Shao, Dongmin, Meng, Chao, Perros, Frederic, Garfield, Benjamin E., Zhu, Jie, Montani, David, Dorfmuller, Peter, Humbert, Marc, Adcock, Ian M., Wort, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574531/ https://www.ncbi.nlm.nih.gov/pubmed/26382031 http://dx.doi.org/10.1186/s12931-015-0262-y

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