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Using mixtures of biological samples as process controls for RNA-sequencing experiments

BACKGROUND: Genome-scale “-omics” measurements are challenging to benchmark due to the enormous variety of unique biological molecules involved. Mixtures of previously-characterized samples can be used to benchmark repeatability and reproducibility using component proportions as truth for the measur...

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Detalles Bibliográficos
Autores principales: Parsons, Jerod, Munro, Sarah, Pine, P. Scott, McDaniel, Jennifer, Mehaffey, Michele, Salit, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574543/
https://www.ncbi.nlm.nih.gov/pubmed/26383878
http://dx.doi.org/10.1186/s12864-015-1912-7