Genomic profiling of a Hepatocyte growth factor-dependent signature for MET-targeted therapy in glioblastoma

BACKGROUND: Constitutive MET signaling promotes invasiveness in most primary and recurrent GBM. However, deployment of available MET-targeting agents is confounded by lack of effective biomarkers for selecting suitable patients for treatment. Because endogenous HGF overexpression often causes autocr...

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Detalles Bibliográficos
Autores principales: Johnson, Jennifer, Ascierto, Maria Libera, Mittal, Sandeep, Newsome, David, Kang, Liang, Briggs, Michael, Tanner, Kirk, Marincola, Francesco M., Berens, Michael E., Vande Woude, George F., Xie, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574608/
https://www.ncbi.nlm.nih.gov/pubmed/26381735
http://dx.doi.org/10.1186/s12967-015-0667-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4574608/
https://www.ncbi.nlm.nih.gov/pubmed/26381735
http://dx.doi.org/10.1186/s12967-015-0667-x

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